MicroRNA let-7: Regulation, single nucleotide polymorphism, and therapy in lung cancer
نویسندگان
چکیده
منابع مشابه
A single nucleotide polymorphism in the promoter region of let-7 family is associated with lung cancer risk in Chinese.
Lung cancer is a complex polygenic disease and many genetic factors are involved in the development of the disease. As one of the most important and widely studied families of microRNA, let-7 appears to play an important role in initiation and progression of lung cancer. Any small changes in miRNA level or its target point can cause significant changes in gene function. In this study, we examin...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2015
ISSN: 0973-1482
DOI: 10.4103/0973-1482.163830